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regeneron faces sales uncertainty while madrigal reports strong drug launch results

Regeneron Pharmaceuticals' shares dropped nearly 10% as third-quarter sales of Eylea fell short of expectations, raising concerns about future sales amid competition. In contrast, Madrigal Pharmaceuticals reported strong sales of its MASH drug, Rezdiffra, totaling $62 million, significantly exceeding forecasts. UCB's Alzheimer’s drug trial showed promising secondary results despite missing its main goal, while AbbVie announced a partnership with EvolveImmune Therapeutics to develop cancer therapies.

wave life sciences reports promising early results in rna editing trial

Wave Life Sciences has reported promising early results from its RNA editing treatment for alpha-1 antitrypsin deficiency (AATD), showing significant increases in AAT protein levels in two patients. This marks a milestone in therapeutic RNA editing, with no serious side effects observed. The findings have boosted investor confidence, leading to a 75% rise in Wave's shares, while GSK prepares to take over development under their partnership.
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